2025 NFL Odds Week 16: Lines, Spreads for all 16 Games

Dec 20, 2025, 5:21 PM

Listen to this article NFL Week 16 kicks off on Thursday, as the Seahawks host the Rams. Here are the lines for every Week 16 matchup at DraftKings Sportsbook as of Dec. 20. This page may contain affiliate links to legal sports betting partners. If you sign up or place a wager, FOX Sports may be com...

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